植入式生理信號無(wú)線(xiàn)遙測系統用于長(cháng)時(shí)間測量清醒無(wú)束縛的大鼠、小鼠、兔子、比格犬、猴子、魚(yú)等多種動(dòng)物的心率、體溫和活動(dòng)量等生理參數。使用此系統可以保證動(dòng)物在籠內自由活動(dòng)，不需要麻醉或束縛，這樣測量到的生理信號更能反映自然狀態(tài)下的動(dòng)物生理狀況?？捎糜谏锕澛裳芯亢拖嚓P(guān)的生命體征監測。

植入式生理信號無(wú)線(xiàn)遙測系統可無(wú)線(xiàn)遙測和記錄實(shí)驗動(dòng)物的：心率、體溫、活動(dòng)量.  

植入式生理信號無(wú)線(xiàn)遙測系統由植入體(E-Mitter)、接收數據轉換器(Receiver)、電纜和記錄分析計算機(VitalView)構成。1厘米大小的植入體E-Mitter集成了傳感器、放大器和無(wú)線(xiàn)信號發(fā)射器，根據測量信號不同有多種規格。植入式E-Mitter轉發(fā)器不需電池，由接收數據轉換器(Receiver)輸出電力。實(shí)驗人員將植入體埋入動(dòng)物皮下，生理信號被植入體采集到并轉換成相應的電信號后用無(wú)線(xiàn)電發(fā)射出來(lái)，由飼養籠下方的接收器接收到并傳遞給數據轉換器，完成數據轉換后送入處理器進(jìn)行數據處理。系統最多可同時(shí)連接32個(gè)接收器，完成大規模的試驗。

植入體(E-Mitter)是植入在動(dòng)物體內的微型設備,它集成了傳感器，放大器，數字轉換，無(wú)線(xiàn)發(fā)射的功能并解決了生物體的抗排異反應。植入體有用于測量生物心率，體溫和活動(dòng)量等多種參數的規格。

 

植入式生理信號無(wú)線(xiàn)遙測系統的主要特點(diǎn)：

? 無(wú)線(xiàn)遙測

? 植入式E-Mitter轉發(fā)器沒(méi)有電池

? 長(cháng)期監測-植入裝置后允許連續、遙測實(shí)驗動(dòng)物一生

? 準確、可靠，報告清醒無(wú)束縛動(dòng)物的生理和行為數據

 

E-Mitter（植入體系統）主要技術(shù)參數:

 

E-Mitter temperature range溫度范圍	33° C - 41° C
E-Mitter accuracy精度	± 0.1° C
G2 E-Mitter size / weight大小/重量	15.5 mm x 6.5 mm 毫米/ 1.1 gm克
G2 HR E-mitter size / weight大小/重量	19.5 mm x 3.5mm毫米/ 1.5 gm克
TA E-Mitter size / weight大小/重量	23 mm x 8 mm毫米/ 1.6 gm克
HR E-Mitter size / weight 大小/重量	26 mm x 8 mm毫米/ 2.2 gm克
HR measuring range心率測量范圍	120 - 780 BPM
Activity活動(dòng)量	Gross motor activity only粗大活動(dòng)

ER4000 信號接收器
ER4000信號接收器，用于給E-Mitters充電和接收E-Mitters傳回來(lái)的測量數據。適合標準的大小鼠飼養籠具。

信號接收器的主要參數

ER-4000Energizer/Receiver尺寸	56 cm x 29 cm x 7 cm
通訊形式	RS 232 串行
激發(fā)接收器數量	32
單個(gè)電源支持激發(fā)接收器數量	4
激發(fā)接收器需要空間	30 cm (水平); 20 cm (垂直)
E-Mitter 傳輸范圍	12 cm above ER-4000

VitalView軟件

激發(fā)接收器和感應器通過(guò)VitalView軟件連接到電腦。最多可以記錄240個(gè)數據通道，典型應用120個(gè)測試對象，對于E-mitter系統最多32個(gè)測試對象。

VitalView軟件可以設置實(shí)驗參數和采集數據。軟件管理與硬件的連接，并且儲存顯示基本的圖形化的數據分析。軟件也提供統計形式的數據顯示，可以輸出數據。

 

Telemetry - used to monitor temperature, gross motor activity and heart rate data. 
Physiological and behavioral monitoring oftransgenic mice and other laboratory animals has never been simpler. Through the use of biotelemetry and a variety of available sensors, it is possible for VitalView to monitor up to seven different physiological or behavioral parameters from a single laboratory subject

Combinations of the following parameters may be monitored for multiple laboratory subjects using VitalView:
Body Core Temperature
Heart Rate
Gross Motor Activity
Running Wheel Turns
Drinking/Licking Frequency
Feeding Behavior
Ambient Temperature
Ambient Light
 
E-Mitter Battery-Free Implantable Transponders：
Using telemetry to provide temperature, gross motor activity and heart rate data. An E-Mitter is a small implantable transponder that is powered by capturing energy from electrical fields generated by the ER-4000 Energizer/Receiver. This allows the E-Mitter to operate without batteries and remain implanted indefinitely to monitor the subject''s temperature, activity or heart rate. As a result, high costs and downtime of explantation, refurbishment and reimplantation are avoided.

如只需要測量大鼠、小鼠的核心體溫，可以選擇植入式體溫膠囊，對體溫數據進(jìn)行遙測：

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